Estimating Empirical Codon Hidden Markov Models
نویسندگان
چکیده
منابع مشابه
Estimating Empirical Codon Hidden Markov Models
Empirical codon models (ECMs) estimated from a large number of globular protein families outperformed mechanistic codon models in their description of the general process of protein evolution. Among other factors, ECMs implicitly model the influence of amino acid properties and multiple nucleotide substitutions (MNS). However, the estimation of ECMs requires large quantities of data, and until ...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2012
ISSN: 1537-1719,0737-4038
DOI: 10.1093/molbev/mss266